Phillex



Composition	Per 24 mg/ml, 0.3% lidocaine	Per 24 mg/ml, 0.3% lidocaine	Per 24 mg/ml, 0.3% lidocaine
Areas of injection	Wrinkles: “crow’s feet”, perioral and periorbital wrinkles, lip contour, neck wrinkles, nasolacrimal groove	Deep naso-labial folds, marionette lines, volume and contour of lips	Deep folds and wrinkles: malar region, chin, cheeks, nasal correction
Injection depth	Epidermis, upper dermis	Middle/deep layer of derma	Deep layer of derma/hypoderm
Syringe volume	1.1 ml	1.1 ml	1.1 ml
Needle size	30G/27G	27G	25G/27G
Storage	-	2-25˚C	-
Duration of procedures	-	12-18 months	-
BDDE	-	not found	-
Shelf life	-	24 months	-



Composition	Per 24 mg/ml, 0.3% lidocaine
Areas of injection	Wrinkles: “crow’s feet”, perioral and periorbital wrinkles, lip contour, neck wrinkles, nasolacrimal groove
Injection depth	Epidermis, upper dermis
Syringe volume	1.1 ml
Needle size	30G/27G
Storage	-
Duration of procedures	-
BDDE	-
Shelf life	-



Composition	Per 24 mg/ml, 0.3% lidocaine
Areas of injection	Deep naso-labial folds, marionette lines, volume and contour of lips
Injection depth	Middle/deep layer of derma
Syringe volume	1.1 ml
Needle size	27G
Storage	2-25˚C
Duration of procedures	12-18 months
BDDE	not found
Shelf life	24 months



Composition	Per 24 mg/ml, 0.3% lidocaine
Areas of injection	Deep folds and wrinkles: malar region, chin, cheeks, nasal correction
Injection depth	Deep layer of derma/hypoderm
Syringe volume	1.1 ml
Needle size	25G/27G
Storage	-
Duration of procedures	-
BDDE	-
Shelf life	-

About PHILLEX

Phillex™ – new generation of intradermal fillers based on stabilized hyaluronic acid of non-animal origin.
Phillex™ – due to innovative method of production it was possible to obtain spherical molecules of hyaluronic acid with higher-order and dense grid (see fig.3).
Phillex™ – first medical product with spatial ordering of molecules of hyaluronic acid (4D-matrix technology). Due to production technology of spherical molecules, PHILLEX not just removes skin defects (3D-matrix mechanism) but also allows to resist compression load (effect of “spring”, 4D-matrix), which, in turn, results in greater facial tissues lifting.
Phillex™ – showed its effectiveness and safety, proved by a series of comparative clinical studies conducted with Restylane (Qmed, Sweden) (see fig.1,2).

Safety and efficiency

Clinical studies results, which have proven their safety and effectiveness

Clinical studies of the medical product Phillex ™ have proven their effectiveness and safety for nasolabial folds correction.

Phillex ™ does not come short to the reference medical product Restylane® (Qmed, Sweden).

Comparative table of GAIS** results, obtained by the researcher on the 8th, 16th, and 24th week of FAS* Fig.1				Comparative table of GAIS** results, obtained by the research subjects on the 8th, 16th, and 24th week of FAS* Fig.2
GAIS**				GAIS**
Period of time	Number of patients	Tested product (PhillexTM Deep)	Control item (Restylane® Deep)	Period of time	Number of patients	Tested product (PhillexTM Deep)	Control item (Restylane® Deep)
Period of time	n	Mean±SD	Mean±SD	Period of time	n	Mean±SD	Mean±SD
8th week	66	2.12±0.48	2.08±0.51	8th week	66	2.15±0.50	2.08±0.51
16th week	66	2.06±0.49	2.02±0.51	16th week	66	2.06±0.49	2.02±0.51
24th week	66	1.65±0.71	1.64±0.72	24th week	66	1.65±0.71	1.64±0.72

Participants of the study

66 participants scored 3 or 4 points by GAIS Scale . Target: eliminate nasolabial folds.

Methodology

Arbitrary sampling; diversified blind study. Control of efficiency and safety of comparing with Restylane® (Q Med, Sweden).

Conclusions

Clinical studies have confirmed that (Deep) is safe and efficient medical product for nasolabial folds correction and does not come short to the reference medical product Restylane®.
1 Results of clinical studies made by Pronexx Co.,Ltd.

* FAS* = a set of data for a full analysis; GAIS Global Aesthetic Improvement Scale

Specific features: 1. Monophasic spherical structure

Phillex™ has a regular, spherical and dense grid comparing with other fillers, ensures continuous and easy injection throughout the entire process of volumization and helps to ensure natural and harmonized appearance.

Specific features: 2. Comparative characteristics of efforts in medical products extrusion for contour correction



Phillex™ – extrusion strength of this medical product allows the doctors to easily and safely control injections throughout the entire procedure.

Specific features: 3. Comparative diagram of pain during injection



Phillex™ –contains 0.3% of lidocaine, which relieves pain suffered by the patients during or after injection; laser needle sharpening allows to minimize pain during initial injection.